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Year Number of Results
2003 1
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2007 1
2008 1
2009 2
2011 1
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2013 1
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2015 1
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2018 2
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2022 3
2024 0

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Page 1
Inflammasome Activation Aggravates Cutaneous Xanthomatosis and Atherosclerosis in ACAT1 (Acyl-CoA Cholesterol Acyltransferase 1) Deficiency in Bone Marrow.
Wakabayashi T, Takahashi M, Yamamuro D, Karasawa T, Takei A, Takei S, Yamazaki H, Nagashima S, Ebihara K, Takahashi M, Ishibashi S. Wakabayashi T, et al. Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):2576-2589. doi: 10.1161/ATVBAHA.118.311648. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354239 Free article.
The present study aimed to clarify the role of NLRP3 inflammasomes in the worsening of atherosclerosis and cutaneous xanthoma induced by ACAT1 deficiency. Approach and Results- Ldlr-null mice were transplanted with bone marrow from WT (wild type) mice and mice lacking A …
The present study aimed to clarify the role of NLRP3 inflammasomes in the worsening of atherosclerosis and cutaneous xanthoma induced by …
Apelin and its receptor APJ in cardiovascular diseases.
Yu XH, Tang ZB, Liu LJ, Qian H, Tang SL, Zhang DW, Tian GP, Tang CK. Yu XH, et al. Clin Chim Acta. 2014 Jan 20;428:1-8. doi: 10.1016/j.cca.2013.09.001. Epub 2013 Sep 18. Clin Chim Acta. 2014. PMID: 24055369 Review.
New insight into the role of lipid metabolism-related proteins in rheumatic heart valve disease.
Xie T, Chen X, Liu C, Cai X, Xiang M, Liu S, Li R, Lin Z, Liu D, Dong M, Chen X, Zou M, Qiao P. Xie T, et al. Lipids Health Dis. 2022 Oct 28;21(1):110. doi: 10.1186/s12944-022-01722-x. Lipids Health Dis. 2022. PMID: 36307855 Free PMC article.
Oil red O staining also revealed the abovementioned results as well as fat cells. Both ABCA1 and ACAT1 were expressed in the rheumatic mitral valve via IHC, whereas only ACAT1 showed a faint level of expression in the ischemic mitral valve with no expression of ABCA …
Oil red O staining also revealed the abovementioned results as well as fat cells. Both ABCA1 and ACAT1 were expressed in the rheumati …
Effect of tumor necrosis factor-alpha on acyl coenzyme A: cholesteryl acyltransferase activity and ACAT1 gene expression in THP-1 macrophages.
He P, Cheng B, Wang Y, Wang H. He P, et al. J Huazhong Univ Sci Technolog Med Sci. 2007 Apr;27(2):170-2. doi: 10.1007/s11596-007-0216-9. J Huazhong Univ Sci Technolog Med Sci. 2007. PMID: 17497288
In order to explore the effect and mechanisms of tumor necrosis factor-alpha (TNF-alpha) on the activity of the acyl coenzyme A: cholesteryl acyltransferase (ACAT), THP-1 monocytes were cultured and induced to differentiate into macrophages with phorbol ester. ...
In order to explore the effect and mechanisms of tumor necrosis factor-alpha (TNF-alpha) on the activity of the acyl coenzyme A: chol …
Fusobacterium nucleatum Accelerates Atherosclerosis via Macrophage-Driven Aberrant Proinflammatory Response and Lipid Metabolism.
Zhou J, Liu L, Wu P, Zhao L, Wu Y. Zhou J, et al. Front Microbiol. 2022 Mar 11;13:798685. doi: 10.3389/fmicb.2022.798685. eCollection 2022. Front Microbiol. 2022. PMID: 35359716 Free PMC article.
The serum levels of pro-atherosclerotic factors, such as interleukin (IL)-6, IL-1beta, tumor necrosis factor (TNF)-alpha, monocyte chemoattractant protein-1 (MCP-1), c-reactive protein, and oxidized low-density lipoprotein (ox-LDL) and microRNAs (miR-146a, miR-155, and miR …
The serum levels of pro-atherosclerotic factors, such as interleukin (IL)-6, IL-1beta, tumor necrosis factor (TNF)-alpha, monocyte ch …
Atheroprotective Effects of Tumor Necrosis Factor-Stimulated Gene-6.
Watanabe R, Watanabe H, Takahashi Y, Kojima M, Konii H, Watanabe K, Shirai R, Sato K, Matsuyama TA, Ishibashi-Ueda H, Iso Y, Koba S, Kobayashi Y, Hirano T, Watanabe T. Watanabe R, et al. JACC Basic Transl Sci. 2016 Oct 31;1(6):494-509. doi: 10.1016/j.jacbts.2016.07.008. eCollection 2016 Oct. JACC Basic Transl Sci. 2016. PMID: 30167534 Free PMC article.
Tumor necrosis factor-stimulated gene-6 (TSG-6), an anti-inflammatory protein, was shown to be localized in the neointima of injury-induced rat arteries. ...
Tumor necrosis factor-stimulated gene-6 (TSG-6), an anti-inflammatory protein, was shown to be localized in the neointima of injury-i …
Lowering the n-6/n-3 PUFAs ratio inhibits the formation of THP-1 macrophage-derived foam cell.
Song Z, Xia H, Yang L, Wang S, Sun G. Song Z, et al. Lipids Health Dis. 2018 May 25;17(1):125. doi: 10.1186/s12944-018-0772-y. Lipids Health Dis. 2018. PMID: 29801502 Free PMC article.
The levels of IL-6 and TNFalpha in supernatant were detected with ELISA methods. The expressions of CD36, ABCA1, ACAT1, PPARgamma and LXRalpha mRNA were detected with real-time PCR. ...CONCLUSIONS: Lowering the ratios of n-6 to n-3 PUFAs can decrease the secretion of infla …
The levels of IL-6 and TNFalpha in supernatant were detected with ELISA methods. The expressions of CD36, ABCA1, ACAT1, PPARgamma and …
Expression of Membrane Bound O-Acyltransferase Domain Containing 7 after Myocardial Infarction and its Role in Lipid Metabolism in vitro.
Li X, Wang Z, Meng H, Meng F, Yang P. Li X, et al. Int J Med Sci. 2022 Mar 14;19(4):609-617. doi: 10.7150/ijms.70614. eCollection 2022. Int J Med Sci. 2022. PMID: 35582424 Free PMC article.
MBOAT7 interference and overexpression vectors were constructed and transfected into L-02 hepatocytes and expression was examined by RT-qPCR and western blotting. The expression of SCAP, LDLR, HMGCR, ACAT1, ABCA1, SREBP1, ACC, FAS, SCD, and PPARgamma in the lipid metabolis …
MBOAT7 interference and overexpression vectors were constructed and transfected into L-02 hepatocytes and expression was examined by RT-qPCR …
Intratumor cholesteryl ester accumulation is associated with human breast cancer proliferation and aggressive potential: a molecular and clinicopathological study.
de Gonzalo-Calvo D, López-Vilaró L, Nasarre L, Perez-Olabarria M, Vázquez T, Escuin D, Badimon L, Barnadas A, Lerma E, Llorente-Cortés V. de Gonzalo-Calvo D, et al. BMC Cancer. 2015 Jun 9;15:460. doi: 10.1186/s12885-015-1469-5. BMC Cancer. 2015. PMID: 26055977 Free PMC article.
RESULTS: Group-wise comparisons, linear regression and logistic regression models showed a close association between CE-rich tumors and higher histologic grade, Ki-67 and tumor necrosis. CE-rich tumors displayed higher mRNA and protein levels of low-density lipoprotein rec …
RESULTS: Group-wise comparisons, linear regression and logistic regression models showed a close association between CE-rich tumors and high …
Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions.
Komeili Movahhed T, Moslehi A, Golchoob M, Ababzadeh S. Komeili Movahhed T, et al. Iran J Basic Med Sci. 2019 Jul;22(7):736-744. doi: 10.22038/ijbms.2019.33553.8012. Iran J Basic Med Sci. 2019. PMID: 32373294 Free PMC article.
RESULTS: Allantoin administration decreased serum alanine aminotransferase (ALT), cholesterol, low-density lipoprotein (LDL), hepatic lipid accumulation, and liver tumor necrosis factor (TNFalpha) level. Also, treatment with allantoin down-regulated the gene expression of …
RESULTS: Allantoin administration decreased serum alanine aminotransferase (ALT), cholesterol, low-density lipoprotein (LDL), hepatic lipid …
20 results